Endocrine Abstracts

Introduction: Consumptive hypothyroidism is a rare condition characterized by the aberrant expression and increased activity of thyroid hormone deiodinase type 3 (DIO3) in neoplastic tissue. This leads to an augmented conversion of thyroxine (T4) to the inactive reverse triiodothyronine (rT3). So far, most cases of consumptive hypothyroidism have been described in infants with hemangiomas.Case presentation: We report the case of a 64-year-old woman with ...

Background: Typing somatostatin receptor (SSTR) expression in neuroendocrine tumors (NETs) is of relevance to target an octreotide-based diagnostic approach and treatment. The expanding use of immunohistochemistry to detect SSTR is to date not paralleled by an accurate methodological setting and standardized interpretation of the results.Objective: A multicentric study was designed to compare SSTR immunohistochemical expression with in vivo scinti...